Dr. Anja Träger
Particle Formulation Group (PFG)
Jena Center for Soft Matter (JCSM)
Friedrich-Schiller-Universität Jena
Philosophenweg 7
07743 Jena
Telefon: +49 3641 9 48 599
Telefax: +49 3641 9 48 202
anja.traeger@uni-jena.de
HomepageExterner Link
Funktionen
- Arbeitsgruppenleiter Parcticle Formulation Group (PFG)
Forschungsgebiete
- Synthesis of polymer-based nanocarriers for gene delivery
- Structure-Property-Relationship of nanocarriers to evaluate stability, toxicity as well as efficiency
- Balancing active and passive targeting strategies for drug and gene delivery
- Transport of different genetic materials (siRNA, mRNA, DNA) for various applications, including therapy and biotechnology
Publikationen (ausgewählte 5 aktuelle)
- J. I. Solomun, L. Martin, P. Mapfumo, E. Moek, E. Amro, F. Becker, S. Tuempel, S. Hoeppener, K. L. Rudolph, A. Traeger, “PH-Sensitive Packaging of Cationic Particles by an Anionic Block Copolymer Shell”, J. Nanobiotechnology 2022, 20, 336
- P. Klemm, J. I. Solomun, M. Rodewald, M. T. Kuchenbrod, V. G. Hänsch, F. Richter, J. Popp, C. Hertweck, S. Hoeppener, C. Bonduelle, S. Lecommandoux, A. Traeger, S. Schubert “Polyplex Surfing as Efficient Gene Delivery Mechanism of Tailored Amphiphilic Polypeptides” Biomacromolecules 2022, 23, 4718-4733
- K. Leer, G. Cinar, J. I. Solomun, L. Martin, I. Nischang, A. Traeger, “Core-crosslinked, temperature- and pH-responsive micelles: Design, physicochemical characterization, and gene delivery application”, Nanoscale 2021, DOI: 10.1039/D1NR04223H
- F. Richter, K. Leer, L. Martin, P. Mapfumo, J. I. Solomun, M. T. Kuchenbrod, S. Hoeppener, J. C. Brendel, A. Traeger, “The impact of anionic polymers on gene delivery: How composition and assembly help evading the toxicity-efficiency dilemma”, J. Nanobiotechnology 2021, 19, 292
- A. T. Press, A. Traeger, C. Pietsch, A. Mosig, M. Wagner, M. G. Clemens, N. Jbeily, N. Koch, M. Gottschaldt, N. Beziere, V. Ermolayev, V. Ntziachristos, J. Popp, M. M. Kessels, B. Qualmann, U. S. Schubert, M. Bauer, "Cell type-specific delivery of short interfering rnas by dye-functionalised theranostic nanoparticles", Nat. Commun. 2014, 5, 5565