Dr. Joachim Clement

Functions

• Research Group Leader Hematology and Internal Oncology

Research

• Innovative nanomaterials in biomedicine
• Identification and characterization of circulating tumor cells and Tomor associated cells
• Tumor biology of bone morphogenesis factors

Publications (selected 5 most recent)

1. Mihajlović, J., Diehl, L.M.A., Hochhaus, A., Clement J.H. 2019. Inhibition of bone morphogenetic protein signaling reduces viability, growth and migratory potential of non-small cell lung carcinoma cells. J. Cancer Res. Clin. Oncol. 145: 2675-2687.
2. Dutz, S., Buske, N., Landers, J., Gräfe, C., Wende, H., Clement, J.H. 2020. Biocompatible magnetic fluids of Co-doped iron oxide nanoparticles with tunable magnetic properties. Nanomaterials: 10: 1019; doi.org/10.3390/nano10061019
3. Ernst, P., Press, A.T., Fischer, M., Schäfer, V., Gräfe, C., Clement, J.H., Ernst, T., Schubert, U.S., Bauer, M., Hochhaus, A. 2020. Polymethine dye-functionalized nanoparticles as a specific drug delivery system for the eradication of CML stem cells. Molecular Therapy – Oncolytics 18: 372-381
4. Gresing, L.J., Radon, P., Friedrich, R.P., Zahn, D., Raasch, M., Mosig, A.S., Dutz, S., Alexiou, C., Wiekhorst, F., Hochhaus, A., Clement, J.H. 2021. Negatively charged magnetic nanoparticles pass the blood-placenta barrier under continuous flow conditions in a time-dependent manner. Journal of Magnetism and Magnetic Materials 521: 167535; doi.org/10.1016/j.jmmm.2020.167535
5. Mickoleit, F., Jörke, C., Richter, R., Rosenfeldt, S., Markert, S., Rehberg, I., Schenk, A.S., Bäumchen, O., Schüler, D., Clement J.H. 2023. Long-term stability, biocompatibility and magnetization of suspensions of isolated bacterial magnetosomes. Small 19: 2006244: DOI: 10.1002/smll.202206244